Psoriasis is a chronic-inflammatory, noncontagious skin disease, manifesting itself primarily in redness and dandruff of the skin. Quite often comorbidities like metabolic syndrome (diabetes mellitus, hypercholesterolemia, hypertension), joint disease (psoriasis arthritis), of cardiovascular system or of the psyche (depression, anxiety states) occur.
Until now, the exact cause of development of psoriasis have not yet been determined. It is expected that a genetic disposition and other factors can increase risk for psoriasis. Such factors are infections and diseases, different foods, certain medication, environmental factors, hormonal fluctuations and stress.
It is also expected that a malfunction of the immune system increases the frequency of skin renewal, leading to strong dandruff of the skin. Interleukins like IL-12, IL-17 and IL-23 as well as tumor necrosis factor (TNF) are involved in different inflammatory processes.
Currently there is no cure for psoriasis patients but many therapeutic options are available. This includes external treatment with creams and ointments as well as treatment with UV rays (phototherapy). Another option are drugs for systemic therapy to slow down or stop inflammatory processes.
In addition, there is a large number of specific monoclonal antibodies against tumor necrosis factor or IL-12, IL-17 or IL-23 which are injected subcutaneously to reduce inflammatory reactions of the skin.
Our nurses can administer the subcutaneous injection at the patients’ home. Patients and their carers can also be trained to self-administer the injections themselves.